Pharmacokinetics, pharmacogenetics, and toxicity of co-administered efavirenz and isoniazid
Background: CYP2B6 slow metabolisers have higher efavirenz concentrations, which are further increased by isoniazid inhibiting efavirenz’s accessory metabolic pathway. Objectives: We investigated the association between CYP2B6 genotype and toxicity in people living with HIV (PLWH) on isoniazid and...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AOSIS
2025-03-01
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| Series: | Southern African Journal of HIV Medicine |
| Subjects: | |
| Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/1661 |
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