Reversible Modulation of Motile Cilia by a Benzo[<i>e</i>][1,2,4]triazinone: A Potential Non-Hormonal Approach to Male Contraception

Reversible Modulation of Motile Cilia by a Benzo[<i>e</i>][1,2,4]triazinone: A Potential Non-Hormonal Approach to Male Contraception

Motile cilia play essential roles in various physiological processes including fluid flow generation and sperm motility. In this study, we identified 1,3-diphenyl-6-(4-phenylpiperazin-1-yl)benzo[<i>e</i>][1,2,4]triazin-7(1<i>H</i>)-one as a potent and reversible modulator of...

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Bibliographic Details
Main Authors: Maria Chatzifrangkeskou, Alexandra Perdiou, Revekka Kreouzou, Georgia A. Zissimou, Dragos F. Flesariu, Panayiotis A. Koutentis, Paris A. Skourides
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
motile cilia
deciliation
<i>Xenopus laevis</i>
transition zone
Online Access:https://www.mdpi.com/2073-4409/14/10/688
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