Fruitless decommissions regulatory elements to implement cell-type-specific neuronal masculinization.

In the fruit fly Drosophila melanogaster, male-specific splicing and translation of the Fruitless transcription factor (FruM) alters the presence, anatomy, and/or connectivity of >60 types of central brain neurons that interconnect to generate male-typical behaviors. While the indispensable funct...

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Bibliographic Details
Main Authors: Margarita V Brovkina, Rachel Duffié, Abbigayl E C Burtis, E Josephine Clowney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009338&type=printable
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