The inflammasome adaptor protein ASC promotes amyloid deposition in cryopyrin-associated periodic syndromes

The inflammasome adaptor protein ASC promotes amyloid deposition in cryopyrin-associated periodic syndromes

In this Correspondence, P. Pelegrin and colleagues found that the deposition of amyloid in tissues in Cryopyrin-Associated Periodic Syndrome were promoted by the extracellular presence of the inflammasome adaptor protein ASC, opening exciting new directions in clinical practice to obtain a novel the...

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Main Authors: Cristina Alarcón-Vila, Laura Hurtado-Navarro, Sandra V Mateo, Alejandro Peñín-Franch, Carlos M Martínez, Cristina Molina-López, María C Baños, Ana I Gómez, Javier Gómez-Román, Alberto Baroja-Mazo, Juan I Arostegui, Natalia Palmou-Fontana, Juan J Martínez-García, Pablo Pelegrin
Format: Article
Language:English
Published: Springer Nature 2024-12-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.1038/s44321-024-00176-1
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https://doi.org/10.1038/s44321-024-00176-1

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