BF3·Et2O Catalysed 4-Aryl-3-phenyl-benzopyrones, Pro-SERMs, and Their Characterization

We have synthesized the novel 4-(4-hydroxy-benzyl)-3-phenyl-chromen-2-one which is a precursor of SERMs with a smaller number of steps and good yield. Two methodologies for the synthesis have been worked out. Anhydrous BF3·Et2O catalyzed reaction was found to be selective for product formation while...

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Bibliographic Details
Main Authors: Ambika Srivastava, Pooja Singh, Rajesh Kumar
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2015/527159
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