β-catenin safeguards cell survival via a transcription-independent mechanism during the induction of primitive streak from hESCs
Abstract The emergence of the primitive streak, representing an organizing center for gastrulation, marks the mesendodermal lineage specification from epiblast, in which the epiblast cells undergo highly organized collective behaviors to form mesendodermal cells properly. Cell death is observed at t...
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| Main Authors: | Peng Zhang, Xu-Xia Li, Hua-Jun Bai, Yongxu Zhao, Senle Rao, He Liang, Xiao-Ling Luo, Huang-Tian Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-025-02559-w |
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