Development and validation of a nomogram for predicting the risk of intestinal barrier dysfunction in patients after major abdominal surgery: a prospective cohort study

Development and validation of a nomogram for predicting the risk of intestinal barrier dysfunction in patients after major abdominal surgery: a prospective cohort study

BackgroundIntestinal barrier dysfunction (IBDF) can lead to systemic inflammatory response syndrome and multiple organ failure, severely jeopardizing patient health. Preventing the occurrence of IBDF is crucial, but effective prediction and assessment tools are currently lacking. In this study, we a...

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Main Authors: Qinghua Zou, Ruotian Wang, Yunfang Dong, Weiming Li, Guoyun Zhao, Zhaochuan Yin, Manqing Hu, Yijun Li, Qingwen Xu, Lixing Wang, Kaiwen Shi, Hongyuan Liu, Yichen Hu, Yuanpei Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Medicine
Subjects:
intestinal barrier dysfunction
abdominal major surgery
gastrointestinal surgery
pancreaticoduodenectomy
nomogram
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1606443/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1606443/full

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