Measuring time saved in Alzheimer's disease: What is a meaningful slowing of progression?

Measuring time saved in Alzheimer's disease: What is a meaningful slowing of progression?

Abstract INTRODUCTION Minimal clinically important differences (MCIDs) for Alzheimer's disease (AD) have previously been estimated using clinician‐based anchors. However, MCIDs have been criticized for not reflecting the preferences of people living with AD (PLWAD). Furthermore, interpretations...

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Main Authors: Krista Lanctot, Linus Jönsson, Alireza Atri, Russ Paulsen, Soeren Mattke, Julie Hviid Hahn‐Pedersen, Pepa Polavieja, Thomas Maltesen, Teresa León, Anders Gustavsson, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
ADNI data
Alzheimer's disease
Clinical Dementia Rating scale—Sum of the Boxes
meaningful within‐person change
minimal clinically important difference
patient perspective
Online Access:https://doi.org/10.1002/trc2.70081
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https://doi.org/10.1002/trc2.70081

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