eNOS activation by HDL is impaired in genetic CETP deficiency.

eNOS activation by HDL is impaired in genetic CETP deficiency.

Mutations in the CETP gene resulting in defective CETP activity have been shown to cause remarkable elevations of plasma HDL-C levels, with the accumulation in plasma of large, buoyant HDL particles enriched in apolipoprotein E. Genetic CETP deficiency thus represents a unique tool to evaluate how s...

Full description

Saved in:
Bibliographic Details
Main Authors: Monica Gomaraschi, Alice Ossoli, Silvia Pozzi, Peter Nilsson, Angelo B Cefalù, Maurizio Averna, Jan Albert Kuivenhoven, G Kees Hovingh, Fabrizio Veglia, Guido Franceschini, Laura Calabresi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0095925
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1371/journal.pone.0095925

Similar Items