Appraising non-linear association between pre-diagnostic platelet counts and cancer survival outcomes: observational and genetic analysis

Appraising non-linear association between pre-diagnostic platelet counts and cancer survival outcomes: observational and genetic analysis

Previous studies have reported inconsistent associations between platelet count (PLT) and cancer survival. However, whether there is linear causal effect merits in-depth investigations. We conducted a cohort study using the UK Biobank and a two-sample Mendelian randomization (MR) analysis. PLT level...

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Bibliographic Details
Main Authors: Changtao Li, Junhua Chen, Deqian Han, Chi Shu, Jun Huang, Linru Wei, Haoran Luo, Qingbin Wu, Xin Chen, Yazhou He, Yanhong Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Platelets
Subjects:
Cancer survival
cohort study
Mendelian randomization
platelet counts
Online Access:https://www.tandfonline.com/doi/10.1080/09537104.2024.2379815
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https://www.tandfonline.com/doi/10.1080/09537104.2024.2379815

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