Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo Oral Nicotine pouches

Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo Oral Nicotine pouches

IntroductionOral nicotine pouches (ONPs) are a newer category of smokeless tobacco products containing pharmaceutical-grade nicotine but no tobacco leaf. These products have the potential to help smokers transition away from cigarettes. To assess their potential role as alternatives to cigarettes, w...

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Bibliographic Details
Main Authors: Milly N. Kanobe, Christie Y. Powell, Makena Patrudu, Sarah A. Baxter, Melissa A. Tapia, John Darnell, Kristen Prevette, Alison G. Gibson, Sarah A. Ayoku, Leanne Campbell, Jeffrey W. Coffield, Brian M. Keyser, Bhagya Sukka Ganesh, Nathan Gale, Kristen G. Jordan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
nicotine uptake
abuse liability
subjective effects
Velo Oral Nicotine pouches
combustible cigarettes
NRT gum
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1547073/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1547073/full

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