Enzyme inhibitory activity of marine alkaloid aaptamines for neurodegenerative diseases: an in silico study

The enzyme inhibitory activities of a dataset of 28 aaptamines are performed to identify potential multifunctional drugs for neurodegenerative diseases (NDs). First, the drug-like properties and pharmacokinetic (ADMET) study excluded seven molecules, mostly for the non-permeability of the blood–brai...

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Bibliographic Details
Main Authors: Thi Le Anh Nguyen, Hoang Linh Nguyen, Thi My Pham, Dinh Hieu Truong, Thi Chinh Ngo, Mai Suan Li, Duy Quang Dao
Format: Article
Language:English
Published: The Royal Society 2025-07-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.250697
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