Folic acid ameliorates high glucose–induced neurotoxicity in human forebrain organoids: Insights from proteomics

Folic acid ameliorates high glucose–induced neurotoxicity in human forebrain organoids: Insights from proteomics

Abstract Pregestational diabetes (PGDM) has been associated with an elevated risk of congenital abnormalities, particularly those affecting the nervous system. The efficacy of folic acid (FA) supplementation in reducing the incidence of neurodevelopmental damage caused by PGDM has been well document...

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Bibliographic Details
Main Authors: Haoni Yan, Shujin Chen, Aynur Abdulla, Zhile Li, Tsz Yui Zhuang, Manlin Zhang, Leqi Wu, Yizhi Zhang, Xianting Ding, Lai Jiang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Food Frontiers
Subjects:
folic acid
forebrain organoids
functional food
high glucose
neurodevelopment
proteomics
Online Access:https://doi.org/10.1002/fft2.470
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https://doi.org/10.1002/fft2.470

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