Simple and Efficient Synthesis of <i>N</i>-Succinimidyl-4-[<sup>18</sup>F]fluorobenzoate ([<sup>18</sup>F]SFB)—An Important Intermediate for the Introduction of Fluorine-18 into Complex Bioactive Compounds

Simple and Efficient Synthesis of <i>N</i>-Succinimidyl-4-[<sup>18</sup>F]fluorobenzoate ([<sup>18</sup>F]SFB)—An Important Intermediate for the Introduction of Fluorine-18 into Complex Bioactive Compounds

<b>Background:</b> <i>N</i>-succinimidyl-[<sup>18</sup>F]fluorobenzoate ([<sup>18</sup>F]SFB) is commonly prepared through a three-step procedure starting from [<sup>18</sup>F]fluoride ion. A number of methods for the single-step radiosynth...

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Bibliographic Details
Main Authors: Viktoriya V. Orlovskaya, Olga S. Fedorova, Nikolai B. Viktorov, Raisa N. Krasikova
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
fluorine-18
copper-mediated radiofluorination
[<sup>18</sup>F]SFB
prosthetic group
one-step synthesis
cartridge-based purification
Online Access:https://www.mdpi.com/1424-8247/17/12/1723
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