ZFHX3 is integral to androgen/AR signaling involving protein association with AR in prostate cancer cells

ZFHX3 is integral to androgen/AR signaling involving protein association with AR in prostate cancer cells

Abstract The androgen receptor (AR) signaling drives prostatic development and carcinogenesis, whereas the zinc finger homeobox 3 (ZFHX3) transcription factor modulates these processes. AR upregulates ZFHX3 transcription, but whether and how ZFHX3 plays a role in the AR signaling is unknown. RNA-seq...

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Bibliographic Details
Main Authors: Xing Fu, Zhiqian Zhang, Rui Chen, Jun A, Na An, Xinxin Tian, Jin-Tang Dong
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
ZFHX3
Androgen
AR
Prostate cancer
KLK3
Transcription
Online Access:https://doi.org/10.1038/s41598-025-05659-w
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https://doi.org/10.1038/s41598-025-05659-w

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