MiR-147b-3p promotes osteogenesis by targeting NDUFA4 and PI3K/AKT pathway

MiR-147b-3p promotes osteogenesis by targeting NDUFA4 and PI3K/AKT pathway

Abstract Background Osteoporosis (OP) is a progressive metabolic bone disease characterized by impaired bone microarchitecture, decreased bone strength, and dysregulated bone remodeling, leading to an increased risk of fractures. Among osteoporotic fractures, osteoporotic vertebral compression fract...

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Bibliographic Details
Main Authors: Yuanyuan Guo, Kai Shen, Zhijie Li, Changchun Niu, Yang Luo
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
MiR-147b-3p
Type I coenzyme dehydrogenase 1α subcomplex 4 (NDUFA4)
Phosphatidylinositol 3-kinase (PI3K)/AKT pathway
Osteogenesis vertebral compression fractures (OVCF)
Online Access:https://doi.org/10.1186/s13018-025-05598-2
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https://doi.org/10.1186/s13018-025-05598-2

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