UFMylation maintains YAP stability to promote vascular endothelial cell senescence

UFMylation maintains YAP stability to promote vascular endothelial cell senescence

Summary: Endothelial cell (EC) senescence is an accomplice for vascular aging, which leads to cardiovascular diseases (CVDs). Evidences showed that Hippo-Yes-associated protein (YAP) signaling pathway plays an essential role in aging-associated CVDs. Here, we reported that YAP was elevated in senesc...

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Bibliographic Details
Main Authors: Yanan Liu, Min Zuo, Aiwei Wu, Zhaoxiang Wang, Siting Wang, Yongping Bai, Junzhi Zhou, Hu Wang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
Biological sciences
Biochemistry
Cell biology
Cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225001142
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http://www.sciencedirect.com/science/article/pii/S2589004225001142

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