Vitamin C Alleviates Heat-Stress-Induced Damages in Pig Thoracic Vertebral Chondrocytes via the Ubiquitin-Mediated Proteolysis Pathway

Vitamin C Alleviates Heat-Stress-Induced Damages in Pig Thoracic Vertebral Chondrocytes via the Ubiquitin-Mediated Proteolysis Pathway

Heat stress can impair organismal growth by inducing ubiquitination, proteasome-mediated degradation, and subsequent cellular damage. Vitamin C (VC) has been shown to potentially mitigate the detrimental effects of abiotic stresses on cells. Nevertheless, the impact of heat stress on growth plate ch...

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Bibliographic Details
Main Authors: Xiaoyang Yang, Yabiao Luo, Mingming Xue, Shuheng Chan, Yubei Wang, Lixian Yang, Longmiao Zhang, Yuxuan Xie, Meiying Fang
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Antioxidants
Subjects:
vitamin C
weighted gene co-expression network analysis
ubiquitin-mediated proteolysis
ubiquitin protein ligase E3A
cell damage
Online Access:https://www.mdpi.com/2076-3921/13/11/1341
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