Abundance of single filamentous bacteria, and expression of differentiated Th17 cells, their signature cytokine IL-17 A, and retinoic acid receptor are predictive of poor rotavirus vaccine take

Abstract Single filamentous bacteria (SFB) have been shown to prevent murine rotavirus (RV) and other mammalian enteric infections, independent of type I and II interferons, by promoting adaptive and innate immunity through differentiation of intestinal Th17 cells, production of immunoglobulin A and...

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Bibliographic Details
Main Authors: Rotondwa Bubuluma, Mapaseka Seheri, Cliff A. Magwira
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Virology Journal
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Online Access:https://doi.org/10.1186/s12985-025-02816-5
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