Pilin antigenic variants impact gonococcal lifestyle and antibiotic tolerance by modulating interbacterial forces.

Type 4 pili (T4P) are multifunctional filaments involved in adhesion, surface motility, biofilm formation, and horizontal gene transfer. These extracellular polymers are surface-exposed and, therefore, act as antigens. The human pathogen Neisseria gonorrhoeae uses pilin antigenic variation to escape...

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Bibliographic Details
Main Authors: Isabelle Wielert, Sebastian Kraus-Römer, Thorsten E Volkmann, Lisa Craig, Paul G Higgins, Berenike Maier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003022
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