Immunogenicity of an Intranasal Dual (Core and Surface)-Antigen Vaccine Against Hepatitis B Virus Enhanced by Carboxyl-Vinyl Polymer Excipients

Immunogenicity of an Intranasal Dual (Core and Surface)-Antigen Vaccine Against Hepatitis B Virus Enhanced by Carboxyl-Vinyl Polymer Excipients

<b>Background:</b> Hepatitis B virus (HBV) is a major cause of morbidity and mortality globally, and chronic infections are associated with cirrhosis and hepatocellular carcinoma. Issues with conventional treatments and vaccines mean there is a need for new therapeutic vaccines, which mu...

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Bibliographic Details
Main Authors: Md Haroon Or Rashid, Fumihiko Yasui, Takahiro Sanada, Risa Kono, Tomoko Honda, Bouchra Kitab, Lipi Akter, Masashi Utsunomiya, Risa Sato, Osamu Yoshida, Yoichi Hiasa, Yasunori Oda, Yasumasa Goh, Takashi Miyazaki, Michinori Kohara, Kyoko Tsukiyama-Kohara
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Vaccines
Subjects:
HBV
CVP
hy-LHBs
HBc
Online Access:https://www.mdpi.com/2076-393X/13/5/464
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