Labelizer: systematic selection of protein residues for covalent fluorophore labeling

Abstract Attaching fluorescent dyes to biomolecules is essential for assays in biology, biochemistry, biophysics, biomedicine and imaging. A systematic approach for the selection of suitable labeling sites in macromolecules, particularly proteins, is missing. We present a quantitative strategy to id...

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Bibliographic Details
Main Authors: Christian Gebhardt, Pascal Bawidamann, Anna-Katharina Spring, Robin Schenk, Konstantin Schütze, Gabriel G. Moya Muñoz, Nicolas D. Wendler, Douglas A. Griffith, Jan Lipfert, Thorben Cordes
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58602-y
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