NSUN5 promotes cholangiocarcinoma progression by enhancing GLS mRNA stabilization

Abstract Background NSUN5, also known as NOP2/Sun domain 5, is a pivotal RNA methyltransferase that catalyzes the formation of 5-methylcytosine (m5C). Cuproptosis, induced by elevated copper concentrations, is under investigation as a potential therapeutic strategy for cancer treatment. Despite this...

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Bibliographic Details
Main Authors: Ming Shu, Kunpeng Guo, Yikai Huang, Weishan Wang
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Online Access:https://doi.org/10.1007/s00432-025-06163-4
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