Multifactorial approach is needed to unravel the maturation phases of human neurons derived from induced pluripotent stem cells

Multifactorial approach is needed to unravel the maturation phases of human neurons derived from induced pluripotent stem cells

Abstract Neurons derived from induced pluripotent stem cells (h-iPSC-Ns) provide an invaluable model for studying the physiological aspects of human neuronal development under healthy and pathological conditions. However, multiple studies have demonstrated that h-iPSC-Ns exhibit a high degree of fun...

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Bibliographic Details
Main Authors: Maissa Ben Mahmoud, Anikó Rátkai, Krisztina Bauer, Norbert Bencsik, Attila Szücs, Katalin Schlett, Krisztián Tárnok
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Induced pluripotent stem cell
Human neuron
Differentiation
Maturation
Electrophysiology
Morphometry
Online Access:https://doi.org/10.1038/s41598-024-81140-4
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https://doi.org/10.1038/s41598-024-81140-4

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