GPR68 Mediates Lung Endothelial Dysfunction Caused by Bacterial Inflammation and Tissue Acidification

GPR68 Mediates Lung Endothelial Dysfunction Caused by Bacterial Inflammation and Tissue Acidification

Tissue acidification resulting from dysregulated cellular bioenergetics accompanies various inflammatory states. GPR68, along with other members of proton-sensing G protein-coupled receptors, responds to extracellular acidification and has been implicated in chronic inflammation-related diseases suc...

Full description

Saved in:
Bibliographic Details
Main Authors: Pratap Karki, Yunbo Ke, Chenou Zhang, Kamoltip Promnares, Yue Li, Charles H. Williams, Charles C. Hong, Konstantin G. Birukov, Anna A. Birukova
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
acidosis
endothelial permeability
inflammation
LPS
GPR68
OGM-8345
Online Access:https://www.mdpi.com/2073-4409/13/24/2125
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2073-4409/13/24/2125

Similar Items