The association between genetic characteristics and treatment failure when switching from biologic disease-modifying antirheumatic drugs/Janus kinase inhibitors in patients with rheumatoid arthritis

The association between genetic characteristics and treatment failure when switching from biologic disease-modifying antirheumatic drugs/Janus kinase inhibitors in patients with rheumatoid arthritis

Genetic polymorphisms in several genes can determine the response to therapy with biologic disease-modifying antirheumatic drugs (bDMARDs) and Janus kinase inhibitors (JAKi) in rheumatoid arthritis (RA).Objective: to determine the association between polymorphisms of genes of IL-6 (rs1800795), IL-6R...

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Bibliographic Details
Main Authors: A. O. Bobkova, A. M. Lila, A. E. Karateev, I. A. Guseva, E. Yu. Samarkina, M. V. Shabatina, N. V. Konovalova, D. A. Varlamov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2025-02-01
Series:Современная ревматология
Subjects:
therapy switching
therapy efficacy
gene polymorphism
biologic disease-modifying antirheumatic drugs
janus kinase inhibitors
Online Access:https://mrj.ima-press.net/mrj/article/view/1697
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