Synthesis of enantiomerically enriched β-substituted analogs of (S)-α-alanine containing 1-phenyl-1H-1,2,3-triazole groups

Synthesis of enantiomerically enriched β-substituted analogs of (S)-α-alanine containing 1-phenyl-1H-1,2,3-triazole groups

Abstract A synthesis of new enantiomerically enriched derivatives of (S)-α-aminopropionic acid, containing in the β-position 1,2,3-triazole groups coupled with a o-, m- and p-substituted phenyl residue, was developed based on Cu(I) catalyzed [3 + 2] cycloaddition of azides with alkynes. As the start...

Full description

Saved in:
Bibliographic Details
Main Authors: Artavazd S. Poghosyan, Emma A. Khachatryan, Anna F. Mkrtchyan, Volodya Mirzoyan, Anahit M. Hovhannisyan, Karapet R. Ghazaryan, Ela V. Minasyan, Peter Langer, Ashot S. Saghyan
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Amino Acids
Subjects:
Enantiomerically enriched amino acid
[3 + 2] cycloaddition
Chiral BPB
Ni(II) square-planar complexes
Online Access:https://doi.org/10.1007/s00726-024-03430-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s00726-024-03430-5

Similar Items