Microplastics Exposure Aggravates Synovitis and Pyroptosis in SLE by Activating NF-κB and NRF2/KEAP1 Signaling

Microplastics Exposure Aggravates Synovitis and Pyroptosis in SLE by Activating NF-κB and NRF2/KEAP1 Signaling

Microplastics (MPs) represent an emerging pollutant capable of entering the human body through the respiratory and digestive systems, thereby posing significant health risks. Systemic lupus erythematosus (SLE) is a complex autoimmune disease that affects multiple organ systems, often presenting with...

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Bibliographic Details
Main Authors: Wenxiang Zeng, Shiqiao He, Ying Zhao, Minjian Jiang, Wenla Wang, Limeng Yang, Weibin Du, Wei Zhuang
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Toxics
Subjects:
<i>MRL</i>/<i>lpr</i> mice
microplastics
synovitis
oxidative stress
cell pyroptosis
NF-κB signaling
Online Access:https://www.mdpi.com/2305-6304/12/12/840
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