PRKDC regulates cGAMP to enhance immune response in lung cancer treatment

BackgroundDespite its involvement in nucleotide metabolism, tumor immune landscape, and immunotherapy response, the role of 2’-3’-cyclic guanosine monophosphate–adenosine monophosphate (2’,3’-cGAMP) in lung adenocarcinoma (LUAD) remails unelucidated. This study aimed to investigate the antitumor eff...

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Bibliographic Details
Main Authors: Zhanghao Huang, Runqi Huang, Jun Zhu, Youlang Zhou, Jiahai Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1497570/full
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