Chemotactic migration of T cells towards dendritic cells promotes the detection of rare antigens.

In many immunological processes chemoattraction is thought to play a role in guiding cells to their sites of action. However, based on in vivo two-photon microscopy experiments in the absence of cognate antigen, T cell migration in lymph nodes (LNs) has been roughly described as a random walk. Altho...

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Bibliographic Details
Main Authors: Renske M A Vroomans, Athanasius F M Marée, Rob J de Boer, Joost B Beltman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1002763
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