The Historical Evolution and Significance of Multiple Sequence Alignment in Molecular Structure and Function Prediction

The Historical Evolution and Significance of Multiple Sequence Alignment in Molecular Structure and Function Prediction

Multiple sequence alignment (MSA) has evolved into a fundamental tool in the biological sciences, playing a pivotal role in predicting molecular structures and functions. With broad applications in protein and nucleic acid modeling, MSAs continue to underpin advancements across a range of discipline...

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Bibliographic Details
Main Authors: Chenyue Zhang, Qinxin Wang, Yiyang Li, Anqi Teng, Gang Hu, Qiqige Wuyun, Wei Zheng
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
pairwise sequence alignment
multiple sequence alignment
protein monomer
protein complex
RNA
protein language model
Online Access:https://www.mdpi.com/2218-273X/14/12/1531
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