A Highly Charged Positive Cage Causes Simultaneous Enhancement of Type‐II and O2‐Independent‐Type‐I Photodynamic Therapy via One‐/Two‐Photon Stimulation and Tumor Immunotherapy via PANoptosis and Ferroptosis

A Highly Charged Positive Cage Causes Simultaneous Enhancement of Type‐II and O2‐Independent‐Type‐I Photodynamic Therapy via One‐/Two‐Photon Stimulation and Tumor Immunotherapy via PANoptosis and Ferroptosis

To solve the oxygen dependence problem of photodynamic therapy (PDT), it is critical to explore photosensitizers that do not rely on O2 molecule to generate reactive oxygen species (ROS). Herein, a stable cationic metal‐organic cage [Pd6(RuLoz3)8](BF4)28 (MOC‐88) that possesses high +28 charges is d...

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Main Authors: Xiao‐Dong Zhang, Hui‐Juan Yu, Shao‐Qi Guan, Yu‐Lin Lu, Yu Zhang, Yin‐Hui Huang, Ya‐Ping Wang, Chen‐Hui Liu, Zhong‐Min Cao, Yu‐Han Qin, Mei Pan, Jun Shen, Cheng‐Yong Su
Format: Article
Language:English
Published: Wiley-VCH 2024-11-01
Series:Small Science
Subjects:
cationic metal‐organic cages
ferroptoses
one‐/two‐photon Type‐I/II photodynamic therapies
PANoptoses
tumor immunotherapies
Online Access:https://doi.org/10.1002/smsc.202400220
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https://doi.org/10.1002/smsc.202400220

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