Intratumoral Fusobacterium nucleatum is associated with better cancer-specific survival in head and neck cancer patients

Intratumoral Fusobacterium nucleatum is associated with better cancer-specific survival in head and neck cancer patients

Background The oral microbiome, particularly Fusobacterium nucleatum (Fn), has been implicated in head and neck cancers (HNC), influencing local immunity and Human Papillomavirus (HPV) status. Here, we evaluated the presence of Fn and its association with HPV infection, TERT promoter (TERTp) mutatio...

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Main Authors: José Guilherme Datorre, Mariana Bisarro dos Reis, Bruna Pereira Sorroche, Gustavo Ramos Teixeira, Silveli Suzuki Hatano, Ana Carolina de Carvalho, Ricardo Ribeiro Gama, Lidia Maria Rebolho Batista Arantes, Rui Manuel Reis
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Oral Microbiology
Subjects:
Fusobacterium nucleatum
head and neck cancer
droplet digital PCR
Brazil
Biomarker
Online Access:https://www.tandfonline.com/doi/10.1080/20002297.2025.2487644
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https://www.tandfonline.com/doi/10.1080/20002297.2025.2487644

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