Potential application of sucrose acetate isobutyrate, and glyceryl monooleate for nanonization and bioavailability enhancement of rivaroxaban tablets

Potential application of sucrose acetate isobutyrate, and glyceryl monooleate for nanonization and bioavailability enhancement of rivaroxaban tablets

This study aimed to investigate the use of Sucrose acetate isobutyrate (SAIB) and Glyceryl monooleate (GMO) as co-formers for creating Cubosomes and SAIB-based nanodispersions of Rivaroxaban (RXB). The process utilized a modified melt dispersion technique with varying polymer: drug ratios (0.5:1, 0....

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Bibliographic Details
Main Authors: Adam A. Al-Shoubki, Mahmoud H. Teaima, Rehab Abdelmonem, Mohamed A. El-Nabarawi, Sammar Fathy Elhabal
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Pharmaceutical Science Advances
Subjects:
Nanonization
Rivaroxaban
Sucrose acetate isobutyrate
Glyceryl monooleate
Bioavailability enhancement
Online Access:http://www.sciencedirect.com/science/article/pii/S2773216923000132
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http://www.sciencedirect.com/science/article/pii/S2773216923000132

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