C. elegans SSNA-1 is required for the structural integrity of centrioles and bipolar spindle assembly

Abstract Centrioles play key roles in mitotic spindle assembly. Once assembled, centrioles exhibit long-term stability, but how stability is achieved and how it is regulated are not completely understood. In this study we show that SSNA-1, the Caenorhabditis elegans ortholog of Sjogren’s Syndrome Nu...

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Main Authors: Jason A. Pfister, Lorenzo Agostini, Lorène Bournonville, Aurélien Perrier, Prabhu Sankaralingam, Zachary G. Bell, Virginie Hamel, Paul Guichard, Christian Biertümpfel, Naoko Mizuno, Kevin F. O’Connell
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59939-0
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