Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia

Vascular dementia (VaD) is a neurodegenerative disorder characterized by chronic oxygen insufficiency, leading to the generation of oxygen-free radicals, inflammatory responses, disturbances in iron metabolism, lipid peroxidation, and other pathological changes that disrupt intracellular homeostasis...

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Bibliographic Details
Main Authors: Xin-yi Zou, Luo-yang Cai, Jin Zhang, Ying Yuan, Jie Song, Zhao-duan Hu, Xiao-feng Ruan, Rui Peng, Xiao-ming Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
heme oxygenase 1
ferroptosis
vascular dementia
oxidative stress
lipid peroxidation
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2025.1585079/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2025.1585079/full

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