The SOX12-YBX1-LDHA signaling axis drives metastasis in papillary thyroid carcinoma

Abstract The sex-determining region Y (SRY)-box (SOX) family plays crucial roles in carcinogenesis and cancer progression. However, the precise function of SOX12 in papillary thyroid carcinoma (PTC) metastasis remains to be investigated. In this study, we analyzed single-cell and bulk RNA sequencing...

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Main Authors: Xianhui Ruan, Yue Huang, Yu Zeng, Zhenhao Zhao, Mei Tao, Zewei Zhao, Yuqi Wang, Guangwei Xu, Wei Zhang, Jialong Yu, Wei Luo, Songfeng Wei, Xichuan Li, Ming Gao, Yang Yu, Peng Li, Xiangqian Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07797-5
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