The role of renal and liver function in clinical ctDNA testing.

The role of renal and liver function in clinical ctDNA testing.

Circulating tumor DNA (ctDNA) has high clinical potential in early cancer detection. The renal system and the liver are involved in clearing circulating cell free DNA (cfDNA) from the blood. Recent studies on mice show that inhibiting the liver's ability to clear cfDNA results in elevated ctDNA...

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Main Authors: Jens Bo Koudahl Conrad, Tenna Vesterman Henriksen, Jesper Berg Nors, Mads Heilskov Rasmussen, Mai-Britt Worm Ørntoft, Nis Hallundbæk Schlesinger, Per Vadgaard Andersen, Kåre Andersson Gotschalck, Claus Lindbjerg Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319194
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https://doi.org/10.1371/journal.pone.0319194

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