Determination of high-grade serous ovarian cancer stem cell-based subtypes and prognostic model and identification of highly expressed VSIG4 and STAB1 in macrophages

Determination of high-grade serous ovarian cancer stem cell-based subtypes and prognostic model and identification of highly expressed VSIG4 and STAB1 in macrophages

Abstract Background Cancer stem cells are associated with tumorigenesis, aggression, and drug resistance. We aimed to identify stem cell-related subtypes and a prognostic tool, and to investigate potential stem cell-related genes contributing to high-grade serous ovarian cancer (HGSOC). Methods Stem...

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Bibliographic Details
Main Authors: Huijuan Wu, Dan Li, Lu Sun, Hualin Song, Ke Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Stem cell
Risk score
Immune cell infiltration
VSIG4
STAB1
Online Access:https://doi.org/10.1186/s13048-025-01747-7
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https://doi.org/10.1186/s13048-025-01747-7

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