The transcription repressor Bach2 is required for maintaining the B-1 cell population by regulating self-renewal

B-1 cells are a distinct lineage of tissue-resident B cells with crucial roles in innate immunity and tissue homeostasis. Mature B-1 cell pools are mostly maintained by self-renewal in their peripheral niches, in a process that is largely uncharacterized. Here, we investigated the role of the transc...

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Bibliographic Details
Main Authors: Seung-Gen Oh, Jeonghyun Noh, Eunkyeong Jang, Jeehee Youn
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1553089/full
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