TIMP1 promotes microglia M2 polarization through MAPK pathway to ameliorate early brain injury after ischemia

Abstract Objective To explore the molecular regulatory mechanisms and biomarkers in regulating early brain injury (EBI) and inflammatory response after ischemic stroke (IS). Methods Gene expression profiles of GSE148350, GSE35338, and GSE58294 were analyzed to screen the core genes involved in EBI a...

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Bibliographic Details
Main Authors: Kangkang Zhao, Zizhao Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Hereditas
Subjects:
Online Access:https://doi.org/10.1186/s41065-025-00491-8
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