Synergistic protective effects of α-tocopherol and zinc sulfate on superoxide dismutase activity and p53 expression in ovarian granulosa cells of lead-exposed female Wistar rats (Rattus norvegicus)

Synergistic protective effects of α-tocopherol and zinc sulfate on superoxide dismutase activity and p53 expression in ovarian granulosa cells of lead-exposed female Wistar rats (Rattus norvegicus)

This study aimed to evaluate the protective effects of α-tocopherol and zinc sulfate on oxidative stress parameters in ovarian granulosa cells of female Wistar rats (Rattus norvegicus) exposed to lead acetate (Pb(C₂H₃O₂)₂). A total of 25 rats were randomly divided into five groups: Control (C), lead...

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Main Authors: iqbal dwi warsito, Suherni Susilowati, Erma Safitri, Ragil Angga Prastiya, Maya Nurwartanti Yunita, Amung Logam Saputro
Format: Article
Language:English
Published: Universitas Airlangga 2025-04-01
Series:Ovozoa: Journal of Animal Reproduction
Subjects:
α-tocopherol
granulosa cells
lead acetate
oxidative stress
p53
zinc sulfate
Online Access:https://e-journal.unair.ac.id/OVZ/article/view/62786
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https://e-journal.unair.ac.id/OVZ/article/view/62786

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