A method for PCR-free library preparation for sequencing palaeogenomes.

In recent years, methodological advances have substantially improved our ability to recover DNA molecules from ancient samples, raising the possibility to sequence palaeogenomes without PCR amplification. Here we present an amplification-free library preparation method based on a benchmark library p...

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Bibliographic Details
Main Authors: Kirstin Henneberger, Axel Barlow, Federica Alberti, Michaela Preick, Silviu Constantin, Doris Döppes, Wilfried Rosendahl, Michael Hofreiter, Johanna L A Paijmans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319573
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