Working in negative space: Type I interferon mediated immuno-modulation through transcriptional suppression in disease and homeostasis

The type I interferon family of cytokines are rapidly produced following innate pattern recognition receptor engagement and establish a critical early state of host defense. Type I interferons act in antiviral immunity as transcriptional activators and the binding of any type I interferon to the com...

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Bibliographic Details
Main Authors: Ella L Brunsting, Darren J Perkins
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/17534259251367263
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