Phenolics from <i>Ilex rotunda</i> Possess Antioxidative Effects and Block Activation of MAPK and NF-κB Signaling by Inhibiting IL-2 Production in CD3/CD28 Activated Jurkat T Cells

Phenolics from <i>Ilex rotunda</i> Possess Antioxidative Effects and Block Activation of MAPK and NF-κB Signaling by Inhibiting IL-2 Production in CD3/CD28 Activated Jurkat T Cells

<i>Ilex rotunda</i>, an evergreen tree in the holly family, is a traditional medicine with a high phenolic content and various pharmacological effects. This study aimed to investigate phenolic constituents from enriched fractions guided by a total phenolic assay along with a feature-base...

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Bibliographic Details
Main Authors: Ducdat Le, Vinhquang Truong, Thinhulinh Dang, Soojung Yu, Thientam Dinh, Mina Lee
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Antioxidants
Subjects:
<i>Ilex rotunda</i>
antioxidant
IL-2
MAPK
NF-κB
phenolics
Online Access:https://www.mdpi.com/2076-3921/14/3/281
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