Reprograming gene expression in ‘hibernating’ C. elegans involves the IRE-1/XBP-1 pathway

In nature, many animals respond to cold by entering hibernation, while in clinical settings, controlled cooling is used in transplantation and emergency medicine. However, the molecular mechanisms that enable cells to survive severe cold are still not fully understood. One key aspect of cold adaptat...

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Bibliographic Details
Main Authors: Melanie Lianne Engelfriet, Yanwu Guo, Andreas Arnold, Eivind Valen, Rafal Ciosk
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/101186
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