Interaction effect between NAFLD severity and high carbohydrate diet on gut microbiome alteration and hepatic de novo lipogenesis

Interaction effect between NAFLD severity and high carbohydrate diet on gut microbiome alteration and hepatic de novo lipogenesis

Nonalcoholic fatty liver disease (NAFLD) is associated with high carbohydrate (HC) intake. We investigated whether the relationship between carbohydrate intake and NAFLD is mediated by interactions between gut microbial modulation, impaired insulin response, and hepatic de novo lipogenesis (DNL). St...

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Main Authors: Hyena Kang, Hyun Ju You, Giljae Lee, Seung Hyun Lee, Taekyeong Yoo, Murim Choi, Sae Kyung Joo, Jeong Hwan Park, Mee Soo Chang, Dong Hyeon Lee, Won Kim, GwangPyo Ko
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Gut Microbes
Subjects:
Nonalcoholic fatty liver disease
gut microbiome
high carbohydrate diet
de novo lipogenesis
liver transcriptome
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2022.2078612
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https://www.tandfonline.com/doi/10.1080/19490976.2022.2078612

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