Ishophloroglucin A Isolated from <i>Ishige okamurae</i> Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropathy

Ishophloroglucin A Isolated from <i>Ishige okamurae</i> Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropathy

<i>Ishige okamurae</i> (<i>I. okamuare</i>), an edible brown alga, is rich in isophloroglucin A (IPA) phlorotannin compounds and is effective in preventing diseases, including diabetes. We evaluated its anti-glycation ability, intracellular reactive oxygen species scavenging...

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Bibliographic Details
Main Authors: Chi-Heung Cho, Min-Gyeong Kim, Bomi Ryu, Sang-Hoon Lee
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Marine Drugs
Subjects:
brown seaweed
diabetic complication
phlorotannin
methylglyoxal-derived advanced glycation end products
mouse glomerular mesangial cells
Online Access:https://www.mdpi.com/1660-3397/23/1/48
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