Longitudinal Changes in Neuroaxonal and Inflammatory CSF Biomarkers in Multiple Sclerosis Patients Undergoing Interferon Beta Therapy

Longitudinal Changes in Neuroaxonal and Inflammatory CSF Biomarkers in Multiple Sclerosis Patients Undergoing Interferon Beta Therapy

<b>Background/Objective:</b> Neurofilament light chain (Nf-L), neurofilament heavy chain (Nf-H), and chitinase 3-like 1 (CHI3L1) are cerebrospinal fluid (CSF) biomarkers of neuroaxonal damage and inflammation in multiple sclerosis (MS). Their longitudinal response to disease-modifying th...

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Bibliographic Details
Main Authors: Simona Petrescu, Maria-Melania Dumitru-Martoiu, Cristina Aura Panea, Charlotte E. Teunissen
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
multiple sclerosis
biomarkers
cerebrospinal fluid
neurofilament light chain
neurofilament heavy chain
CHI3L1
Online Access:https://www.mdpi.com/2227-9059/13/6/1394
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