USP9X suppresses ferroptosis in diabetic kidney disease by deubiquitinating Nrf2 in vitro

Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates many critical genes associated with iron storage and transportation, the activity of which is influenced by E3 ligase-mediated ubiquitination. We wondered whether there is a deubiquitinase that mediates the deubiquitination of Nrf2 to stab...

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Bibliographic Details
Main Authors: Ningjun Shao, Kedan Cai, Yue Hong, Lingping Wu, Qun Luo
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
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Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2458761
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